MOTS-c

MOTS-c is a 16 amino acid peptide encoded by mitochondrial DNA, the genes inside the part of the cell that makes energy. Research has focused on how the body handles sugar, insulin, and exercise.

Metabolic Peptide

Mitochondrial Support

Our MOTS-c comes as a 20 mg multi-dose vial for subcutaneous injection, compounded by a licensed 503A pharmacy and labeled with your directions. Your prescriber sets the dose and schedule that fit your goals.

Interested in MOTS-c? Start an online consultation with a licensed physician. Your price includes the consultation, and if your prescription is approved, we compound your MOTS-c and our pharmacist will walk you through how to use it.

*Photos of models, not actual patients

*MOTS-c is a compounded product and has not been approved by the FDA. Not for resale.

Pricing

$242

Start Consultation

For Your Doctor

MOTS-c 2 mg/mL Injectable, 10 mL Vial (20 mg): $242

For subcutaneous or intramuscular use

Directions as written by the prescriber

Patient information

What is this medication used for?

• It is prescribed to support healthy metabolism and energy.

• It is prescribed to support how the body uses sugar.

• It may be prescribed for other reasons.

Before you start

• Tell your prescriber about all of your medications, supplements, and health conditions.

• Tell your prescriber if you have ever had cancer.

• Tell your prescriber if you are pregnant, planning a pregnancy, or breastfeeding.

• Tell your prescriber if you take insulin or other medication for blood sugar.

Using your MOTS-c

• Use exactly as written on your prescription label.

• Inject just under the skin or into the muscle as directed. Use a new needle each time and rotate injection sites. Our pharmacist will show you how.

• Store as directed on your label and keep out of reach of children.

Possible side effects

Many people have no side effects or only minor ones. Call your prescriber or get medical help if any of these bother you or do not go away:

• Redness, itching, or soreness where you inject

• Tiredness

• Shakiness, sweating, or hunger, which can be signs of low blood sugar

Get medical help right away for signs of an allergic reaction, such as rash, hives, swelling of the face or throat, or trouble breathing.

Report a problem

Let our pharmacist know about any problems with your medication.

This is a compounded drug product. Not for resale.

Mechanism of Action

MOTS-c works mainly in skeletal muscle, the body’s largest user of sugar. By switching on AMPK, it pushes muscle cells toward burning glucose and fat for fuel, the same direction exercise pushes them.

This is why MOTS-c is sometimes described as an exercise mimetic, though it does not replace the many other benefits of physical activity.

How It Is Given

MOTS-c is given as a small injection just under the skin or into the muscle using an insulin-type syringe. Your prescriber sets the dose and schedule.

Getting the Most From It

MOTS-c is studied as a support for healthy metabolism, not a substitute for it. Regular movement, sleep, and nutrition still matter most.

The Use of Compounded MOTS-c

Background

Most of the body’s proteins come from DNA in the cell nucleus. MOTS-c is one of a small group of peptides coded by DNA inside the mitochondria, the part of the cell that makes energy. Researchers first described it in 2015, and found that levels tend to fall with age and rise with exercise.

How It Is Thought to Work

In animal studies, MOTS-c activates AMPK, an enzyme that acts as the cell’s energy sensor. That shift helps muscle take up glucose and use fuel more efficiently. Under stress, MOTS-c can also move into the cell nucleus and influence which genes are switched on.

What It Has Been Studied For

Mouse studies have looked at diet related weight gain, insulin resistance, age related decline in physical capacity, and bone health.

A version of MOTS-c has been tested in early human trials. Research on the compounded peptide in people is still early.

Safety and Side Effects

MOTS-c has not been through large human safety trials. Reported side effects include injection site redness and tiredness.

If you take medication for diabetes, tell your prescriber, since MOTS-c is studied for its effect on blood sugar.

Summary

MOTS-c is one of the newer peptides people ask about, with promising animal research and limited human data. Your prescriber can help you decide if it fits your plan.

Forest Park Pharmacy

COST-PLUS & COMPOUNDING

MOTS-c

Metabolic Peptide

Pricing

For Your Doctor