Semax

Semax is a seven amino acid peptide built from a fragment of ACTH, a hormone made by the pituitary gland. It has been used for decades as a nasal spray, with research on attention, memory, and stroke recovery.

Cognitive Peptide

Nasal Spray

Our Semax comes as a 1 mg/mL nasal spray, compounded by a licensed 503A pharmacy and labeled with your directions. No injections needed. Your prescriber decides how many sprays and how often.

Want to know if Semax is a fit for you? Start an online consultation with a licensed physician. Your price includes the consultation, and if your prescription is approved, we compound your Semax nasal spray for you.

*Photos of models, not actual patients

*Semax is a compounded product and has not been approved by the FDA. Not for resale.

Pricing

$173

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For Your Doctor

Semax 1 mg/mL Nasal Spray, 6 mL (6 mg): $173

For intranasal use

Directions as written by the prescriber

Patient information

What is this medication used for?

• It is prescribed to support focus, attention, and memory.

• It may be prescribed for other reasons.

Before you start

• Tell your prescriber about all of your medications, supplements, and health conditions.

• Tell your prescriber if you have ever had cancer.

• Tell your prescriber if you are pregnant, planning a pregnancy, or breastfeeding.

• Tell your prescriber about any medications for mood, sleep, or attention.

Using your Semax

• Use exactly as written on your prescription label.

• Spray into the nose as directed. Do not share your spray with anyone.

• Store as directed on your label and keep out of reach of children.

Possible side effects

Many people have no side effects or only minor ones. Call your prescriber or get medical help if any of these bother you or do not go away:

• Mild nose irritation or dryness

• Runny nose

• Headache

Get medical help right away for signs of an allergic reaction, such as rash, hives, swelling of the face or throat, or trouble breathing.

Report a problem

Let our pharmacist know about any problems with your medication.

This is a compounded drug product. Not for resale.

Mechanism of Action

BDNF, or brain-derived neurotrophic factor, works like fertilizer for nerve cells. It helps them form new connections and protects them under stress. Animal studies show Semax increases BDNF in areas of the brain involved in memory and attention.

Semax does not act like a stimulant. Its effects are thought to come from supporting the brain’s own signaling over time.

Why a Nasal Spray

The lining of the nose has a rich blood supply and a short path to the brain. A nasal spray lets Semax be absorbed without injections and without passing through the stomach, where peptides are broken down.

How to Use a Nasal Spray

Gently blow your nose first. Keep your head upright, insert the tip into one nostril, close the other, and spray while breathing in gently. Your prescriber will tell you how many sprays and how often.

The Use of Compounded Semax

Background

Semax was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences in the 1980s. Researchers took a short piece of ACTH, a hormone made by the pituitary gland, and added three amino acids to make it last longer in the body. The result keeps some of ACTH’s effects on the brain without its effects on the adrenal glands.

How It Is Thought to Work

In animal studies, Semax raises levels of BDNF, a protein that supports the growth and survival of nerve cells. It also appears to influence dopamine and serotonin signaling. These findings come mostly from lab and animal research.

What It Has Been Studied For

In Russia, Semax has been studied and used for ischemic stroke, cognitive problems, and some optic nerve conditions.

Research on attention and memory in healthy people is limited, and few studies have been done outside Russia.

Safety and Side Effects

In published studies, Semax has generally been well tolerated. The most common side effect is mild nasal irritation.

Tell your prescriber about any medications that affect mood or brain chemistry.

Summary

Semax has a long history of use in one country and limited research elsewhere. Your prescriber can help you decide whether it makes sense for you.

Forest Park Pharmacy

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Semax

Cognitive Peptide

Pricing

For Your Doctor